Kinetic Properties of an RNA Enzyme That Undergoes Self-Sustained Exponential Amplification

Self-sustained replication of an RNA enzyme.

An RNA enzyme that catalyzes the RNA-templated joining of RNA was converted to a format whereby two enzymes catalyze each other's synthesis from a total of four oligonucleotide substrates. These cross-replicating RNA enzymes undergo self-sustained exponential amplification in the absence of proteins or other biological materials. Amplification occurs with a doubling time of about 1 hour and can...

An Enzyme That Oversees RNA Quality Control

0929 IM model has required the assumption that all of the populations were constant in size, and therefore it has not been useful for assessing how descendant populations arose or changed in size. Hey analyzed DNA sequences from nine loci, so that the population genetic history could be found despite the variation among genes. He also added an additional parameter to the standard IM model to in...

Self-sustained amplification of disturbances in pipe Poiseuille flow

The nonlinear development of disturbances in pipe Poiseuille flow is studied with a low-dimensional model. The basic system from which the model is derived governs disturbances closely related to the radial velocity and radial vorticity disturbances. The analysis is restricted to the interaction of the two first harmonics of streamwise elongated disturbances since they are the most transiently ...

Kinetic Modelling of a Self-sustained Tea Co, Laser

In order to predict the time behaviour of the gain and output power of a TEA CO, laser detailed knowledge is required of the time behaviour of the gas discharge. At a specified time the values of the current and the voltage determine the electron density and the electron energy distribution function; these two quantities determine the excitation rates to the various excitation levels relevant f...

The self-sustained sequence replication amplification system--move over, PCR.